Funded Biotechnology Startups in Spain
Among the 50 most recent biotechnology funding rounds in Spain with disclosed amounts, Ona Therapeutics’ $87M Series B (2026-06-04) is the clear size outli…
Among the 50 most recent biotechnology funding rounds in Spain with disclosed amounts, Ona Therapeutics’ $87M Series B (2026-06-04) is the clear size outlier: it sits well above the next-largest disclosed rounds such as Splice Bio’s $135M (2025-06-11) and Universal Diagnostics’ $35M (2026-01-20), and it exceeds the $41M ARTHEx Biotech (2025-09-17) while most other disclosed rounds cluster in the low single-digit millions or under $25M (e.g., iPremom $3M on 2026-06-30; Impetux Optics $3M on 2026-05-04). The list also shows time concentration in mid-2025 to mid-2026, with multiple Barcelona/Catalonia-based entries appearing alongside the largest rounds (Splice Bio $135M on 2025-06-11; Seqera $26M on 2025-05-06; Gate2Brain $8M on 2026-06-08). Geography is heavily Barcelona-leaning across many rounds (e.g., Ona Therapeutics, Gate2Brain, Impetux Optics, INBRAIN Neuroelectronics) rather than spread evenly across Spain. Stage naming is mixed: “Series Unknown” appears repeatedly and “undisclosed” funding amounts occur alongside disclosed entries (e.g., Biohope undisclosed on 2026-05-14).
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Frequently asked
Which disclosed round is largest, and how different is it from the rest?
The largest disclosed round is Splice Bio’s $135M Series B on 2025-06-11. That dwarfs other high disclosed rounds like Ona Therapeutics’ $87M Series B on 2026-06-04 and Universal Diagnostics’ $35M on 2026-01-20, while many disclosed rounds elsewhere fall around $1M–$8M (for example, Devicare $1M on 2026-02-09 and iPremom $3M on 2026-06-30).
Do recent rounds cluster in time, or are they spread evenly across years?
Rounds shown span from 2023-05-08 (Qubiotech, undisclosed) to the most recent 2026-06-30 (iPremom, $3M). There is noticeable density from mid-2025 through mid-2026, including multiple Barcelona/Catalonia entries in June 2026 (e.g., Ona Therapeutics 2026-06-04 $87M and Gate2Brain 2026-06-08 $8M) and additional large checks in May–June 2025 (Seqera $26M on 2025-05-06; Splice Bio $135M on 2025-06-11).
Is any city over-represented compared to other geographies?
Barcelona/Catalonia appears repeatedly across different rounds and stages, including Gate2Brain (2026-06-08, $8M), Ona Therapeutics (2026-06-04, $87M), Impetux Optics (2026-05-04, $3M), INBRAIN Neuroelectronics (2025-05-06, $5M), and Minoryx Therapeutics (2025-07-10, $31M). Other cities show up with fewer entries, such as Madrid (e.g., Universal Diagnostics 2026-01-20 $35M; 60Nd 2026-02-10 $3M) and Seville (Universal Diagnostics 2026-01-20 $35M).
How much of the dataset is missing stage or amount disclosure?
Stage information is often “Series Unknown” across many entries (for example, iPremom on 2026-06-30 and Gate2Brain on 2026-06-08). Disclosed funding amounts coexist with “undisclosed” amounts (e.g., Biohope undisclosed on 2026-05-14; HEALTH IN CODE undisclosed on 2026-02-12; Trovant Technology undisclosed on 2024-07-24), which limits clean comparisons of size outliers to only rows with disclosed amounts.
Are there any small-round outliers worth flagging against the smallest disclosed amount?
The smallest disclosed amount is $100K at Evolving Therapeutics (Angel) on 2025-01-21. The rest of the disclosed set tends to sit higher in the $1M–$8M range for multiple companies (e.g., Devicare $1M on 2026-02-09; 60Nd $3M on 2026-02-10; Bioinspired Materials $840K on 2025-05-20 is close but still above $100K), making $100K a clear low-end outlier.
What stage mix shows up most around the largest checks?
The biggest disclosed rounds are tied to labeled stages rather than “Series Unknown”: Splice Bio is a Series B ($135M on 2025-06-11), Ona Therapeutics is a Series B ($87M on 2026-06-04), and ARTHEx Biotech is a Series B ($41M on 2025-09-17). In contrast, many other entries with smaller disclosed amounts—such as iPremom ($3M on 2026-06-30) and Vytrus Biotech ($2M on 2026-01-14)—are categorized as “Series Unknown,” suggesting large-money rounds cluster disproportionately among explicitly named stages.
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