Acelot: Funding, Investors & Team (Oct 2026)
Acelot is treating functional protein misfolding diseases where the appropriate therapeutic mechanism is a restoration of the normal protein homeostasis. Functional misfolded proteins are found in various diseases such as ALS, FTD, Parkinson’s, diabetes and cancer. Acelot’s platform combines generative AI, molecular dynamics simulations and proprietary assays to discover small molecules that restore the homeostasis of misfolded proteins in various diseases. We have a pipeline of hit-to-lead discovery compounds across multiple indications, along with an IND-ready candidate for ALS. Our platform was invented by UCSB Computer Science Professor Dr. Ambuj Singh. Acelot’s first development candidate, ACE-2223, is a first-in-class orally bioavailable small molecule that will undergo IND-enabling studies in 2024. ACE-2223 disrupts the misfolded forms of TDP43 and restores functional TDP43. It acts upon the misfolded conformations of TDP43 found across various patient populations, including ALS, FTD and Alzheimer’s. ACE-2223 has excellent brain penetrance and ADME properties. Acelot also has a robust discovery pipeline.
Acelot has raised $4.0M across 1 funding round on record, the most recent a Seed of $4.0M announced in Nov 2024.
That round is below the $8.1M median round size for Biotechnology companies tracked on FundedIQ over the last two years.
Acelot Company Profile and Key Stats
Latest funding round on record: Nov 2024.
Acelot Funding Rounds
Acelot Founders and Leadership Team
No contact details are on record for this team yet.
Acelot Funding Compared to Other Biotechnology Startups
Acelot's latest round of $4.0M is below the median round in Biotechnology. Medians cover the last 24 months of disclosed rounds.
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Acelot Funding FAQs
What does Acelot do?
Acelot is treating functional protein misfolding diseases where the appropriate therapeutic mechanism is a restoration of the normal protein homeostasis. Functional misfolded proteins are found in various diseases such as ALS, FTD, Parkinson’s, diabetes and cancer. Acelot’s platform combines generative AI, molecular dynamics simulations and proprietary assays to discover small molecules that restore the homeostasis of misfolded proteins in various diseases. We have a pipeline of hit-to-lead discovery compounds across multiple indications, along with an IND-ready candidate for ALS. Our platform was invented by UCSB Computer Science Professor Dr. Ambuj Singh. Acelot’s first development candidate, ACE-2223, is a first-in-class orally bioavailable small molecule that will undergo IND-enabling studies in 2024. ACE-2223 disrupts the misfolded forms of TDP43 and restores functional TDP43. It acts upon the misfolded conformations of TDP43 found across various patient populations, including ALS, FTD and Alzheimer’s. ACE-2223 has excellent brain penetrance and ADME properties. Acelot also has a robust discovery pipeline.
How much funding has Acelot raised?
Acelot has raised $4.0M across 1 round on record. The most recent is a Seed of $4.0M announced in Nov 2024.
When did Acelot last raise funding?
Acelot's most recent funding round on record is a Seed of $4.0M, announced in Nov 2024.
Who founded Acelot?
FundedIQ lists Joydeb Mukherjee (Founder) at Acelot.
Where is Acelot headquartered?
Acelot is based in Santa Barbara, California, United States.
How many employees does Acelot have?
Acelot is in the 1-10 employee band.
How does Acelot's funding compare to other Biotechnology startups?
Acelot's latest round of $4.0M is below the $8.1M median round size for Biotechnology companies on FundedIQ across 4,185 tracked companies over the last two years.
About FundedIQ's Acelot Funding Data
FundedIQ tracks announced funding rounds and refreshes this profile every week. Round dates, stages and amounts are normalised to a single format, converted to US dollars, and de-duplicated: two records of the same round announced days apart are merged, and two genuinely different rounds are kept apart on the amounts they disclose. Amounts shown are the disclosed figures only — a round announced without a number is listed and excluded from the total rather than estimated.
Employee counts are reported bands, not exact headcounts. Founder and executive names carry the job title on record. Anything we do not hold for Acelot is left off this page rather than filled in.
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