City Therapeutics: Funding, Investors & Team (Sep 2026)
Founded by pioneering executives and scientists in RNAi, City Therapeutics is advancing next-generation engineering of small interfering RNAs (siRNAs) – the “trigger” molecules that mediate RNAi – to improve and expand the reach of RNAi-based medicines. City’s mission is to build the leading next-generation RNAi therapeutics company, unlocking RNAi’s transformative potential to help patients with a wide range of diseases.
City Therapeutics has raised $235M across 2 funding rounds on record, the most recent a Series B of $99.5M announced in Jun 2026.
That round is above the $8.0M median round size for Biotechnology companies tracked on FundedIQ over the last two years.
City Therapeutics Company Profile and Key Stats
Latest funding round on record: Jun 2026.
City Therapeutics Funding Rounds
City Therapeutics raised $135M in a Series A announced in Oct 2024.
1.7 years later, a Series B of $99.5M was announced in Jun 2026.
City Therapeutics Founders and Leadership Team
Contact details for the City Therapeutics team: 1 of 2 have an email address on file.
Start 14-day free trial →City Therapeutics Funding Compared to Other Biotechnology Startups
City Therapeutics' latest round of $99.5M is above the median round in Biotechnology. Medians cover the last 24 months of disclosed rounds.
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City Therapeutics Funding FAQs
What does City Therapeutics do?
Founded by pioneering executives and scientists in RNAi, City Therapeutics is advancing next-generation engineering of small interfering RNAs (siRNAs) – the “trigger” molecules that mediate RNAi – to improve and expand the reach of RNAi-based medicines. City’s mission is to build the leading next-generation RNAi therapeutics company, unlocking RNAi’s transformative potential to help patients with a wide range of diseases.
How much funding has City Therapeutics raised?
City Therapeutics has raised $235M across 2 rounds on record. The most recent is a Series B of $99.5M announced in Jun 2026.
When did City Therapeutics last raise funding?
City Therapeutics' most recent funding round on record is a Series B of $99.5M, announced in Jun 2026.
Who founded City Therapeutics?
FundedIQ lists Andy Orth (Founder), Sebastian Trousil (Founder) at City Therapeutics.
Where is City Therapeutics headquartered?
City Therapeutics is based in Cambridge, Massachusetts, United States.
How many employees does City Therapeutics have?
City Therapeutics is in the 11-50 employee band.
How does City Therapeutics' funding compare to other Biotechnology startups?
City Therapeutics' latest round of $99.5M is above the $8.0M median round size for Biotechnology companies on FundedIQ across 4,179 tracked companies over the last two years.
About FundedIQ's City Therapeutics Funding Data
FundedIQ tracks announced funding rounds and refreshes this profile every week. Round dates, stages and amounts are normalised to a single format, converted to US dollars, and de-duplicated: two records of the same round announced days apart are merged, and two genuinely different rounds are kept apart on the amounts they disclose. Amounts shown are the disclosed figures only — a round announced without a number is listed and excluded from the total rather than estimated.
Employee counts are reported bands, not exact headcounts. Founder and executive names carry the job title on record. Anything we do not hold for City Therapeutics is left off this page rather than filled in.
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