SetPoint Medical: Funding, Investors & Team (Oct 2026)
SetPoint Medical is dedicated to treating patients with debilitating inflammatory diseases, such as Crohn's Disease and rheumatoid arthritis, using proprietary implantable bioelectronic devices. The company developing novel bioelectronic medicine therapies to treat those who suffer from autoimmune diseases such as rheumatoid arthritis, Crohn's Disease, and multiple sclerosis. The scientific platform is based on the Inflammatory Reflex—the natural mechanism by which the central nervous system regulates the immune system. This mechanism was discovered by SetPoint co-founder Kevin Tracey and published in Nature in May 2000. Since then, the Inflammatory Reflex has been characterized in more than 100 peer reviewed papers in leading scientific journals. Anti-inflammatory potency comparable to leading drugs has been demonstrated in multiple animal models. The company is currently conducting human trials in rheumatoid arthritis at four European centers. SetPoint's microregulator is intended to supplement the body's natural Inflammatory Reflex by providing 'built-in' therapy at a lower cost and with improved safety compared with drugs or biologic solutions.
SetPoint Medical has raised $294M across 4 funding rounds on record, the most recent a Series D of $115M announced in Aug 2025.
That round is above the $8.4M median round size for Biotechnology companies tracked on FundedIQ over the last two years.
SetPoint Medical Company Profile and Key Stats
Latest funding round on record: Aug 2025.
SetPoint Medical Funding Rounds
SetPoint Medical raised $64.0M in an undisclosed round announced in Jan 2021.
6 months later, a Debt Financing of $35.0M was announced in Jul 2021.
1.5 years later, an undisclosed round of $80.0M was announced in Jan 2023.
2.6 years later, a Series D of $115M was announced in Aug 2025.
SetPoint Medical Founders and Leadership Team
Contact details for the SetPoint Medical team: 1 of 3 have an email address on file.
Start 14-day free trial →SetPoint Medical Funding Compared to Other Biotechnology Startups
SetPoint Medical's latest round of $115M is above the median round in Biotechnology. Medians cover the last 24 months of disclosed rounds.
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SetPoint Medical Funding FAQs
What does SetPoint Medical do?
SetPoint Medical is dedicated to treating patients with debilitating inflammatory diseases, such as Crohn's Disease and rheumatoid arthritis, using proprietary implantable bioelectronic devices. The company developing novel bioelectronic medicine therapies to treat those who suffer from autoimmune diseases such as rheumatoid arthritis, Crohn's Disease, and multiple sclerosis. The scientific platform is based on the Inflammatory Reflex—the natural mechanism by which the central nervous system regulates the immune system. This mechanism was discovered by SetPoint co-founder Kevin Tracey and published in Nature in May 2000. Since then, the Inflammatory Reflex has been characterized in more than 100 peer reviewed papers in leading scientific journals. Anti-inflammatory potency comparable to leading drugs has been demonstrated in multiple animal models. The company is currently conducting human trials in rheumatoid arthritis at four European centers. SetPoint's microregulator is intended to supplement the body's natural Inflammatory Reflex by providing 'built-in' therapy at a lower cost and with improved safety compared with drugs or biologic solutions.
How much funding has SetPoint Medical raised?
SetPoint Medical has raised $294M across 4 rounds on record. The most recent is a Series D of $115M announced in Aug 2025.
When did SetPoint Medical last raise funding?
SetPoint Medical's most recent funding round on record is a Series D of $115M, announced in Aug 2025.
Who founded SetPoint Medical?
FundedIQ lists Kevin Tracey (Founder), Shaw Warren (Founder) at SetPoint Medical.
Who is the CEO of SetPoint Medical?
Murthy Simhambhatla is listed as CEO at SetPoint Medical.
Where is SetPoint Medical headquartered?
SetPoint Medical is based in Valencia, California, United States.
How many employees does SetPoint Medical have?
SetPoint Medical is in the 11-50 employee band.
How does SetPoint Medical's funding compare to other Biotechnology startups?
SetPoint Medical's latest round of $115M is above the $8.4M median round size for Biotechnology companies on FundedIQ across 4,185 tracked companies over the last two years.
About FundedIQ's SetPoint Medical Funding Data
FundedIQ tracks announced funding rounds and refreshes this profile every week. Round dates, stages and amounts are normalised to a single format, converted to US dollars, and de-duplicated: two records of the same round announced days apart are merged, and two genuinely different rounds are kept apart on the amounts they disclose. Amounts shown are the disclosed figures only — a round announced without a number is listed and excluded from the total rather than estimated.
Employee counts are reported bands, not exact headcounts. Founder and executive names carry the job title on record. Anything we do not hold for SetPoint Medical is left off this page rather than filled in.
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