FundedIQ
Biotechnology

Spruce Biosciences: Funding, Investors & Team (Sep 2026)

A clinical-stage biopharmaceutical business called Spruce Biosciences is dedicated to creating cutting-edge treatments for uncommon endocrine system illnesses.

www.sprucebiosciences.com LinkedIn San Francisco, United States 11-50 employees
Biopharma Biotechnology Health Care Pharmaceutical
Total raised
$252M
Rounds
5
Latest
Undisclosed round
Apr 2026

Spruce Biosciences has raised $252M across 5 funding rounds on record, the most recent an undisclosed round of $60.0M announced in Apr 2026.

That round is above the $8.0M median round size for Biotechnology companies tracked on FundedIQ over the last two years.

Spruce Biosciences Company Profile and Key Stats

Total funding raised
$252M
across 5 rounds on record
Funding rounds on record
5
1 with no disclosed amount
Latest funding round
Undisclosed round
$60.0M in Apr 2026
Employees
11-50
reported band
Headquarters
San Francisco, United States

Latest funding round on record: Apr 2026.

Spruce Biosciences Funding Rounds

Date
Round
Amount
Undisclosed round
$60.0M
Undisclosed round
Undisclosed
Undisclosed round
$50.0M
Undisclosed round
$53.6M
Undisclosed round
$88.0M

1 of 5 rounds was announced without a disclosed amount and is excluded from the total.

Spruce Biosciences raised $88.0M in an undisclosed round announced in Feb 2020.

3 years later, an undisclosed round of $53.6M was announced in Feb 2023.

2.7 years later, an undisclosed round of $50.0M was announced in Oct 2025.

3 months later, an undisclosed round was announced in Jan 2026 with no disclosed amount.

3 months later, an undisclosed round of $60.0M was announced in Apr 2026.

Spruce Biosciences Founders and Leadership Team

Name
Role
Contact
Alexis Howerton
Founder
Javier Szwarcberg
Founder
Locked

Contact details for the Spruce Biosciences team: 1 of 2 have an email address on file.

Start 14-day free trial →

Spruce Biosciences Funding Compared to Other Biotechnology Startups

Segment
Companies
Median round
4,179
$8.0M
29,722
$7.5M

Spruce Biosciences' latest round of $60.0M is above the median round in Biotechnology. Medians cover the last 24 months of disclosed rounds.

Funded Startups Like Spruce Biosciences in Biotechnology and San Francisco

Companies Similar to Spruce Biosciences

Noveome Biotherapeutics, Inc. is an advanced biopharmaceutical company that focuses on groundbreaking…

Convertible Note $6.8M

XiltriX North America is an information technology company that specializes in monitoring, predictive…

Undisclosed round $3.0M

Novir is an emerging diagnostic biotechnology company with an unmatched team of professionals and trusted…

Seed $3.1M

Abcuro’s mission is to develop a new class of immune-modulatory bio-therapeutics for treating both…

Series D $66.0M

Georgiamune Inc. is a privately-owned biotechnology company that specializes in advanced immunotherapy…

Series B $92.7M

Bridge to Life was founded with the mission of improving organ transplants by licensing and developing new…

Series C $110M

InduPro is a biotechnology firm that focuses on protein therapeutics and technologies related to cell-surface…

Series B $77.0M

Paterna BioSciences, Inc. is a pioneering biotechnology company dedicated to solving the significant…

Series A $6.3M

Legendary Bio's solidarity is a determined spotlight on introducing another period of quality guideline.

Series C $90.0M

Cataract surgery is the single most common procedure performed in the United States annually. Despite…

Series A $7.0M

InSitu Biologics is a developer of a drug delivery platform designed to focus on development of new and…

Convertible Note $1.3M

Remedium Bio is a gene therapy company in the Boston area that is dedicated to developing cures for severe…

Series A $10.0M

Spruce Biosciences Funding FAQs

What does Spruce Biosciences do?

A clinical-stage biopharmaceutical business called Spruce Biosciences is dedicated to creating cutting-edge treatments for uncommon endocrine system illnesses.

How much funding has Spruce Biosciences raised?

Spruce Biosciences has raised $252M across 5 rounds on record. The most recent is an undisclosed round of $60.0M announced in Apr 2026.

When did Spruce Biosciences last raise funding?

Spruce Biosciences' most recent funding round on record is an undisclosed round of $60.0M, announced in Apr 2026.

Who founded Spruce Biosciences?

FundedIQ lists Alexis Howerton (Founder), Javier Szwarcberg (Founder) at Spruce Biosciences.

Where is Spruce Biosciences headquartered?

Spruce Biosciences is based in San Francisco, California, United States.

How many employees does Spruce Biosciences have?

Spruce Biosciences is in the 11-50 employee band.

How does Spruce Biosciences' funding compare to other Biotechnology startups?

Spruce Biosciences' latest round of $60.0M is above the $8.0M median round size for Biotechnology companies on FundedIQ across 4,179 tracked companies over the last two years.

About FundedIQ's Spruce Biosciences Funding Data

FundedIQ tracks announced funding rounds and refreshes this profile every week. Round dates, stages and amounts are normalised to a single format, converted to US dollars, and de-duplicated: two records of the same round announced days apart are merged, and two genuinely different rounds are kept apart on the amounts they disclose. Amounts shown are the disclosed figures only — a round announced without a number is listed and excluded from the total rather than estimated.

Employee counts are reported bands, not exact headcounts. Founder and executive names carry the job title on record. Anything we do not hold for Spruce Biosciences is left off this page rather than filled in.

14-day free trial · Cancel anytime

Know who just raised. Then know who to reach.

Every newly funded startup with its round, its investors and its founders: delivered weekly by email, or searchable in the app.

Alerts from $19/mo · Pro from $99/mo. Card required, nothing charged until day 15, and we email you 3 days before that.