FundedIQ
Biotechnology

Spruce Biosciences: Funding, Investors & Team (Oct 2026)

A clinical-stage biopharmaceutical business called Spruce Biosciences is dedicated to creating cutting-edge treatments for uncommon endocrine system illnesses.

www.sprucebiosciences.com LinkedIn San Francisco, United States 11-50 employees
Biopharma Biotechnology Health Care Pharmaceutical
Total raised
$252M
Rounds
5
Latest
Undisclosed round
Apr 2026

Spruce Biosciences has raised $252M across 5 funding rounds on record, the most recent an undisclosed round of $60.0M announced in Apr 2026.

That round is above the $8.4M median round size for Biotechnology companies tracked on FundedIQ over the last two years.

Spruce Biosciences Company Profile and Key Stats

Total funding raised
$252M
across 5 rounds on record
Funding rounds on record
5
1 with no disclosed amount
Latest funding round
Undisclosed round
$60.0M in Apr 2026
Employees
11-50
reported band
Headquarters
San Francisco, United States

Latest funding round on record: Apr 2026.

Spruce Biosciences Funding Rounds

Date
Round
Amount
Undisclosed round
$60.0M
Undisclosed round
Undisclosed
Undisclosed round
$50.0M
Undisclosed round
$53.6M
Undisclosed round
$88.0M

1 of 5 rounds was announced without a disclosed amount and is excluded from the total.

Spruce Biosciences raised $88.0M in an undisclosed round announced in Feb 2020.

3 years later, an undisclosed round of $53.6M was announced in Feb 2023.

2.7 years later, an undisclosed round of $50.0M was announced in Oct 2025.

3 months later, an undisclosed round was announced in Jan 2026 with no disclosed amount.

3 months later, an undisclosed round of $60.0M was announced in Apr 2026.

Spruce Biosciences Founders and Leadership Team

Name
Role
Contact
Alexis Howerton
Founder
—
Javier Szwarcberg
Founder
Locked

Contact details for the Spruce Biosciences team: 1 of 2 have an email address on file.

Start 14-day free trial →

Spruce Biosciences Funding Compared to Other Biotechnology Startups

Segment
Companies
Median round
4,185
$8.4M
30,319
$7.7M

Spruce Biosciences' latest round of $60.0M is above the median round in Biotechnology. Medians cover the last 24 months of disclosed rounds.

Funded Startups Like Spruce Biosciences in Biotechnology and San Francisco

Companies Similar to Spruce Biosciences

Prolific Machines is a biotech company located in San Francisco, California, that was established in 2020. It…

Series B $50.0M

Altay Therapeutics is a biotech company focused on finding and discovering small molecule therapies for…

Series A $37.0M
Series B $150M

Kallyope, we believe that the gut is the gateway to our internal world. Containing millions of neurons, the…

Undisclosed round $94.0M

Astrocyte Pharmaceuticals is a drug development company that helps in the recovery and well-being of brain…

Series B $9.5M

Tiny Health offers a gut health test specifically designed for mothers and babies aged 0 to 3 years.…

Series B $33.0M

Junevity is dedicated to using cutting-edge transcription factor medicines to combat age-related diseases.…

Undisclosed round —

Arkea Bio creates technology aimed at reducing greenhouse gas (GHG) emissions in the agricultural sector.

Series A $15.0M

Serán is a contract development and manufacturing organization providing a comprehensive suite of…

Private Equity —

Precision’s goal is to provide breakthrough treatments for the one billion patients worldwide suffering from…

Series D $250M

Enveda is a biotechnology company that utilizes AI-powered tools to explore and characterize molecules from…

Series E $311M

Avery Therapeutics, Inc. is a company dedicated to developing tissue engineered therapeutics to treat…

Undisclosed round $8.5M

Spruce Biosciences Funding FAQs

What does Spruce Biosciences do?

A clinical-stage biopharmaceutical business called Spruce Biosciences is dedicated to creating cutting-edge treatments for uncommon endocrine system illnesses.

How much funding has Spruce Biosciences raised?

Spruce Biosciences has raised $252M across 5 rounds on record. The most recent is an undisclosed round of $60.0M announced in Apr 2026.

When did Spruce Biosciences last raise funding?

Spruce Biosciences' most recent funding round on record is an undisclosed round of $60.0M, announced in Apr 2026.

Who founded Spruce Biosciences?

FundedIQ lists Alexis Howerton (Founder), Javier Szwarcberg (Founder) at Spruce Biosciences.

Where is Spruce Biosciences headquartered?

Spruce Biosciences is based in San Francisco, California, United States.

How many employees does Spruce Biosciences have?

Spruce Biosciences is in the 11-50 employee band.

How does Spruce Biosciences' funding compare to other Biotechnology startups?

Spruce Biosciences' latest round of $60.0M is above the $8.4M median round size for Biotechnology companies on FundedIQ across 4,185 tracked companies over the last two years.

About FundedIQ's Spruce Biosciences Funding Data

FundedIQ tracks announced funding rounds and refreshes this profile every week. Round dates, stages and amounts are normalised to a single format, converted to US dollars, and de-duplicated: two records of the same round announced days apart are merged, and two genuinely different rounds are kept apart on the amounts they disclose. Amounts shown are the disclosed figures only — a round announced without a number is listed and excluded from the total rather than estimated.

Employee counts are reported bands, not exact headcounts. Founder and executive names carry the job title on record. Anything we do not hold for Spruce Biosciences is left off this page rather than filled in.

14-day free trial · Cancel anytime

Know who just raised. Then know who to reach.

Startup funding intelligence on every funded startup: the round, the investors and the founders, as a file in your inbox or searchable in the app.

Radar from $49/mo · Pro from $149/mo. Card required, nothing charged until day 15, and we email you 3 days before that. Need something specific? Custom plans from $499/mo.