FundedIQ
Biotechnology

Xilio Therapeutics: Funding, Investors & Team (Oct 2026)

Xilio Therapeutics is a biotechnology company advancing next-generation cancer immunotherapies designed to improve patient outcomes by unleashing the power of the immune system selectively at the site of the tumor. The company’s tumor-selective immunotherapies are based on its proprietary technology, which maximizes the potency of proven immuno-oncology therapies and restricts their activity to the tumor to minimize peripheral side effects. The broad applicability of these therapies across cancer types means that all patients could benefit from these potentially curative medicines. These tumor-selective therapies are designed to overcome the significant toxicities associated with validated IO therapies, such as IL-2 and aCTLA4, which have historically limited the number of patients that can be treated and prevented patients from completing full courses of treatment Xilio Therapeutics proprietary technology enables the explosion of therapeutic activity specifically within the tumor while reducing toxicity throughout the body a nod to the company name, Xilio, derived from the Latin term, Ex Nihilo, meaning creation or big-bang. The company applying its technology to build a broad pipeline of engineered antibodies, cytokines and chemokines as potential new options for people living with cancer. Xilio Therapeutics was founded in 2016 and is headquartered in Waltham, Massachusetts, United States.

www.akriveiatx.com LinkedIn Waltham, United States 51-100 employees
Biotechnology Health Care Health Diagnostics Therapeutics
Total raised
$95.0M
Rounds
1
Latest
Series C
Feb 2021

Xilio Therapeutics has raised $95.0M across 1 funding round on record, the most recent a Series C of $95.0M announced in Feb 2021.

That round is above the $8.1M median round size for Biotechnology companies tracked on FundedIQ over the last two years.

Xilio Therapeutics Company Profile and Key Stats

Total funding raised
$95.0M
across 1 round on record
Funding rounds on record
1
Latest funding round
Series C
$95.0M in Feb 2021
Employees
51-100
reported band
Headquarters
Waltham, United States

Latest funding round on record: Feb 2021.

Xilio Therapeutics Funding Rounds

Date
Round
Amount
Series C
$95.0M

Xilio Therapeutics Founders and Leadership Team

Name
Role
Contact
Rene Russo
CEO
—

No contact details are on record for this team yet.

Xilio Therapeutics Funding Compared to Other Biotechnology Startups

Segment
Companies
Median round
4,185
$8.1M
30,234
$7.6M
1,869
$60M

Xilio Therapeutics' latest round of $95.0M is above the median round in Biotechnology. Medians cover the last 24 months of disclosed rounds.

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Xilio Therapeutics Funding FAQs

What does Xilio Therapeutics do?

Xilio Therapeutics is a biotechnology company advancing next-generation cancer immunotherapies designed to improve patient outcomes by unleashing the power of the immune system selectively at the site of the tumor. The company’s tumor-selective immunotherapies are based on its proprietary technology, which maximizes the potency of proven immuno-oncology therapies and restricts their activity to the tumor to minimize peripheral side effects. The broad applicability of these therapies across cancer types means that all patients could benefit from these potentially curative medicines. These tumor-selective therapies are designed to overcome the significant toxicities associated with validated IO therapies, such as IL-2 and aCTLA4, which have historically limited the number of patients that can be treated and prevented patients from completing full courses of treatment Xilio Therapeutics proprietary technology enables the explosion of therapeutic activity specifically within the tumor while reducing toxicity throughout the body a nod to the company name, Xilio, derived from the Latin term, Ex Nihilo, meaning creation or big-bang. The company applying its technology to build a broad pipeline of engineered antibodies, cytokines and chemokines as potential new options for people living with cancer. Xilio Therapeutics was founded in 2016 and is headquartered in Waltham, Massachusetts, United States.

How much funding has Xilio Therapeutics raised?

Xilio Therapeutics has raised $95.0M across 1 round on record. The most recent is a Series C of $95.0M announced in Feb 2021.

When did Xilio Therapeutics last raise funding?

Xilio Therapeutics' most recent funding round on record is a Series C of $95.0M, announced in Feb 2021.

Who is the CEO of Xilio Therapeutics?

Rene Russo is listed as CEO at Xilio Therapeutics.

Where is Xilio Therapeutics headquartered?

Xilio Therapeutics is based in Waltham, Massachusetts, United States.

How many employees does Xilio Therapeutics have?

Xilio Therapeutics is in the 51-100 employee band.

How does Xilio Therapeutics' funding compare to other Biotechnology startups?

Xilio Therapeutics' latest round of $95.0M is above the $8.1M median round size for Biotechnology companies on FundedIQ across 4,185 tracked companies over the last two years.

About FundedIQ's Xilio Therapeutics Funding Data

FundedIQ tracks announced funding rounds and refreshes this profile every week. Round dates, stages and amounts are normalised to a single format, converted to US dollars, and de-duplicated: two records of the same round announced days apart are merged, and two genuinely different rounds are kept apart on the amounts they disclose. Amounts shown are the disclosed figures only — a round announced without a number is listed and excluded from the total rather than estimated.

Employee counts are reported bands, not exact headcounts. Founder and executive names carry the job title on record. Anything we do not hold for Xilio Therapeutics is left off this page rather than filled in.

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