Series E Funded Startups in United States
Across the 50 most recent Series E rounds in the United States shown here, Lambda’s $1.5B (2025-11-18) and Groq’s $750M (2025-09-21) sit far above the rest…
Across the 50 most recent Series E rounds in the United States shown here, Lambda’s $1.5B (2025-11-18) and Groq’s $750M (2025-09-21) sit far above the rest of the disclosed amounts; the next-largest disclosed figure below them is $300M (e.g., Deel $300M on 2025-10-16, Abridge $300M on 2025-06-24, and Filevine $260M on 2025-09-22). The smallest disclosed amount is $5M for Ghost Autonomy (2023-11-08), highlighting a wide dispersion from single-digit millions up to the billion-dollar range.
The deals cluster heavily in California: multiple entries are based in San Francisco/San Francisco-area cities (e.g., Lambda 2025-11-18; Deel 2025-10-16; EvenUp 2025-10-10; Supabase 2025-10-01; Filevine 2025-09-22 in Salt Lake City, but many others are Bay Area), while New York and Massachusetts also recur (e.g., EliseAI $250M on 2025-08-19 in New York; Carmot Therapeutics $150M on 2023-05-25 in Berkeley; Vedanta Biosciences $107M on 2023-04-25 in Cambridge). Temporally, the list spans 2022-11-15 (CG Oncology $120M) through 2025-11-18 (Lambda), with a denser run from 2024-11-13 (Beta Bionics $60M) into late 2025.
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Frequently asked
How does the largest disclosed Series E round compare to the rest of the list’s disclosed amounts?
Lambda’s $1.5B on 2025-11-18 is the clear outlier, with Groq at $750M on 2025-09-21 also in the billion-dollar range; the next disclosed amounts fall notably lower, with multiple rounds clustered around $300M (e.g., Deel $300M on 2025-10-16 and Abridge $300M on 2025-06-24).
Which rounds look like outliers on the low end, and where do they sit versus the rest?
Ghost Autonomy’s $5M on 2023-11-08 is the smallest disclosed amount in the rows shown. Most other disclosed rounds are well above that floor, such as PM Pediatrics at $50M (2023-06-20) and Glowforge at $20M (2023-05-17).
Are there sectors that recur enough to suggest a cluster in this Series E set?
Artificial Intelligence appears repeatedly (e.g., Lambda $1.5B on 2025-11-18; Groq $750M on 2025-09-21; EvenUp $150M on 2025-10-10; SandboxAQ $150M on 2025-04-04), and Biotechnology also recurs across many different states and cities (e.g., Alzheon $100M on 2024-06-12; Carmot Therapeutics $150M on 2023-05-25; CG Oncology $120M on 2022-11-15).
Is there evidence of geographic concentration by state or city?
California is over-represented by sheer frequency across entries (e.g., San Francisco: Lambda $1.5B on 2025-11-18, Deel $300M on 2025-10-16, and EvenUp $150M on 2025-10-10; Palo Alto: PsiQuantum $1.0B on 2025-09-09 and SandboxAQ $150M on 2025-04-04). Massachusetts and New York also show multiple entries, such as Boston/Cambridge/Waltham-area biotech and EliseAI in New York ($250M on 2025-08-19).
What does the most recent window (roughly the last 90 days) suggest about timing?
The most recent entries run through November 2025, including Lambda $1.5B on 2025-11-18 and Ursa Major $100M on 2025-11-17, followed by multiple late-2025 rounds like Groq $750M (2025-09-21) and EvenUp $150M (2025-10-10). Earlier years extend back to at least 2022-11-15 with CG Oncology ($120M), indicating a broad temporal span rather than a single burst limited to one year.
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