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Funded Startups in South Dakota

The largest disclosed round in this South Dakota snapshot is SAB Biotherapeutics’ $130M (2023-10-02), which dwarfs the next-largest disclosed amounts in th…

The largest disclosed round in this South Dakota snapshot is SAB Biotherapeutics’ $130M (2023-10-02), which dwarfs the next-largest disclosed amounts in the table—$35M (Dakota Gold, 2025-03-20) and $22M (Prismatic, 2024-01-17). Most disclosed rounds cluster far lower: several are in the $1M–$15M band, and only one entry appears above $50M.

The dates span 2020-07-17 (SAB Biotherapeutics, $14M) through 2025-08-27 (All Kids Bike, $90K), with noticeable concentration in late 2023: four rounds land on 2023-11-09 (Elevate Rapid City $100K; Enterprise Institute $360K) and 2023-10-02/$2023-10-20 (SAB Biotherapeutics $130M; Great Plains Bank $12M). Sector-wise, Biotechnology appears 2+ times (SAB Biotherapeutics twice; Inanovate once), and “Series Unknown” is the dominant classification, appearing in 12 of 14 rows; the only non-“Series Unknown” items are Prismatic (Series B, $22M on 2024-01-17) and Property Meld (Series B, $15M on 2023-01-25), plus one row with an explicitly “undisclosed” amount (Query.AI, 2024-09-25). Geographically, Sioux Falls shows up repeatedly (Prismatic, SAB Biotherapeutics, Inanovate), alongside Rapid City (All Kids Bike, Elevate Rapid City) and Brookings (Query.AI, Enterprise Institute).

Most recent rounds

14 shown

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Frequently asked

What stands out as the largest disclosed round, and how does it compare to the rest of the disclosed amounts?

SAB Biotherapeutics’ $130M on 2023-10-02 is the clear outlier here: it sits well above the next-largest disclosed amounts of $35M (Dakota Gold, 2025-03-20) and $22M (Prismatic, 2024-01-17). Most other disclosed rounds fall between $90K and $15M (for example, All Kids Bike $90K on 2025-08-27 and Golden West Telecommunications $5M on 2023-05-04).

Do the most recent rounds cluster in a narrow time window, or are they evenly spread?

The 14 rows span from 2020-07-17 to 2025-08-27, but they are not evenly distributed: late 2023 contains multiple close-dated entries, including 2023-11-09 (Elevate Rapid City $100K and Enterprise Institute $360K) plus nearby October 2023 rounds (SAB Biotherapeutics $130M on 2023-10-02 and Great Plains Bank $12M on 2023-10-20).

Which cities show up repeatedly, suggesting a local cluster rather than one-off activity?

Sioux Falls appears most consistently across different companies: Prismatic ($22M on 2024-01-17), SAB Biotherapeutics ($130M on 2023-10-02 and $14M on 2020-07-17), and Inanovate ($2M on 2022-10-06). Rapid City also repeats with All Kids Bike ($90K on 2025-08-27) and Elevate Rapid City ($100K on 2023-11-09). Brookings is another recurring node with Query.AI (undisclosed, 2024-09-25) and Enterprise Institute ($360K, 2023-11-09).

What stage mix is visible in these recent entries, and how much of it is “Series Unknown”?

“Series Unknown” dominates, appearing in 12 of 14 rows; that leaves only two rows explicitly marked as Series B (Prismatic $22M on 2024-01-17, and Property Meld $15M on 2023-01-25). One additional row uses “Venture - Series Unknown” (Inanovate, $2M on 2022-10-06), and Query.AI (2024-09-25) is the only entry shown as undisclosed amount.

Are there meaningful sector outliers or a clear sector concentration?

Sectors are mostly dispersed across the list, but Biotechnology is one of the few recurring categories (SAB Biotherapeutics twice: $130M on 2023-10-02 and $14M on 2020-07-17; plus Inanovate $2M on 2022-10-06). The other high-ticket amount tied to a different sector is Dakota Gold’s $35M in Natural Resources (2025-03-20), which is much larger than most non-Biotech disclosed rounds in the table.

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